Rational Chemical Design of Molecular Glue Degraders
Rational Chemical Design of Molecular Glue Degraders
Engineered Glucose Oxidase-Carbon Nanotube Conjugates for Tissue-Translatable Glucose Nanosensors
Engineered Glucose Oxidase-Carbon Nanotube Conjugates for Tissue-Translatable Glucose Nanosensors
Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases
Mechanosensitive stem cell fate choice is instructed by dynamic fluctuations in activation of Rho GTPases
p300 is an obligate integrator of combinatorial transcription factor inputs
p300-chromatin binding requires multiple TF-interaction domains
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
LYCHOS, a lysosomal protein, senses cholesterol and activates mTORC1 signaling by binding GATOR1, linking cholesterol to cell growth regulation.
The viral packaging motor potentiates Kaposi's sarcoma-associated herpesvirus gene expression late in infection
ORF29, a viral DNA packaging motor subunit, also enhances late gene transcription in KSHV, linking viral packaging and gene expression.
Identification of structurally diverse FSP1 inhibitors that sensitize cancer cells to ferroptosis
Identification of structurally diverse small molecule inhibitors of ferroptosis target FSP1
Orphan quality control shapes network dynamics and gene expression
Orphan quality control shapes network dynamics and gene expression
Expanding the substrate scope of PylRS enzymes to include non-⍺-amino acids in vitro and in vivo
Expanding the substrate scope of PylRS enzymes to include non-⍺-amino acids in vitro and in vivo
Genome expansion by a CRISPR trimmer-integrase
CRISPR systems lacking Cas4 use fused or recruited exonucleases for faithful acquisition of new CRISPR immune sequences
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes
Peptide-mediated delivery of CRISPR enzymes for the efficient editing of primary human lymphocytes